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|Section2= }} Trimethylamine ''N''-oxide (TMAO) is the organic compound in the class of amine oxides with the formula (CH3)3NO. This colorless solid is usually encountered as the dihydrate. It is a product of the oxidation of trimethylamine and a common metabolite in animals. It is an osmolyte found in saltwater fish, sharks, rays, molluscs, and crustaceans. It is a protein stabilizer that may serve to counteract urea, the major osmolyte of sharks, skates and rays. It is also higher in deep-sea fishes and crustaceans, where it may counteract the protein-destabilizing effects of pressure. TMAO decomposes to trimethylamine (TMA), which is the main odorant that is characteristic of degrading seafood. ==Synthesis== Treatment of aqueous trimethylamine with hydrogen peroxide affords the dihydrate (Me = CH3):〔A. J. Pearson "Trimethylamine N-Oxide" in Encyclopedia of Reagents for Organic Synthesis John Wiley & Sons, 2001: New York. 〕 :H2O2 + Me3N → H2O + Me3NO Trimethylamine-''N''-oxide is biosynthesized from trimethylamine, which is derived from choline. 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Trimethylamine N-oxide」の詳細全文を読む スポンサード リンク
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