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・ Trimethobenzamide
・ Trimethoprim
・ Trimethoprim/polymyxin
・ Trimethoprim/sulfamethoxazole
・ Trimethoxyamphetamine
・ Trimethoxyphenethylamine
・ Trimethyl ammonium compounds
・ Trimethyl borate
・ Trimethyl orthoformate
・ Trimethyl phosphate
・ Trimethyl phosphite
・ Trimethylaluminium
・ Trimethylamine
・ Trimethylamine dehydrogenase
・ Trimethylamine monooxygenase
Trimethylamine N-oxide
・ Trimethylamine N-oxide reductase
・ Trimethylamine-corrinoid protein Co-methyltransferase
・ Trimethylamine-N-oxide reductase
・ Trimethylamine-N-oxide reductase (cytochrome c)
・ Trimethylamine-oxide aldolase
・ Trimethylaminuria
・ Trimethylarsine
・ Trimethylarsine (data page)
・ Trimethylbenzenes
・ Trimethylborane
・ Trimethyldiborane
・ Trimethyldiphenylpropylamine
・ Trimethylene carbonate
・ Trimethylenemethane


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Trimethylamine N-oxide : ウィキペディア英語版
Trimethylamine N-oxide

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Trimethylamine ''N''-oxide (TMAO) is the organic compound in the class of amine oxides with the formula (CH3)3NO. This colorless solid is usually encountered as the dihydrate. It is a product of the oxidation of trimethylamine and a common metabolite in animals. It is an osmolyte found in saltwater fish, sharks, rays, molluscs, and crustaceans. It is a protein stabilizer that may serve to counteract urea, the major osmolyte of sharks, skates and rays. It is also higher in deep-sea fishes and crustaceans, where it may counteract the protein-destabilizing effects of pressure. TMAO decomposes to trimethylamine (TMA), which is the main odorant that is characteristic of degrading seafood.
==Synthesis==
Treatment of aqueous trimethylamine with hydrogen peroxide affords the dihydrate (Me = CH3):〔A. J. Pearson "Trimethylamine N-Oxide" in Encyclopedia of Reagents for Organic Synthesis John Wiley & Sons, 2001: New York. 〕
:H2O2 + Me3N → H2O + Me3NO
Trimethylamine-''N''-oxide is biosynthesized from trimethylamine, which is derived from choline.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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